c3po costume smoking a cigarette C-3PO Penkmatters shirt, hoodie, sweater, longsleeve and V-neck T-shirt Meet Anthony Daniels, the guy

Dimensions: 4090 x 2000 px | 34.6 x 16.9 cm | 13.6 x 6.7 inches | 300dpi Date taken: May 2013 Photographer: Zoonar/Petr Malyshev More information: cigar with a wooden mouthpiece, isolated on white

The transition is complex and multifaceted, but the direction towards a market with a greater emphasis on alternatives to combustible cigarettes is clear

Lung cancer in the era of precision medicine

ETHICAL APPROVAL AND INFORMED CONSENT All participants provided electronic informed consent and UK Biobank received ethical approval from the North-West Multi-center Research Ethics Committee (MREC) covering the whole of UK